Progene from Progene Healthcare

Progene Review – Should You Trust This Supplement?

What Is Progene?

Progene is a testosterone-boosting supplement that is made in the USA. The product has been on the market for more than eleven years, and the manufacturer’s website seems to imply that it is recommended by some physicians. It has a huge number of ingredients, especially compared to competitor’s products. Although some ingredients are probably very effective, others are useless. Be warned that this testosterone booster contains DHEA, which is not only a banned substance in sports competitions but is potentially dangerous.

This product is likely to be effective for most healthy men, but will be especially effective for men who have a nutrient deficiency or who have provably low testosterone levels. However, the manufacturer warns that the product may not suitable for those with certain medical issues or who take certain medications. Seek more information on the manufacturer’s website to see whether this warning applies to you. If it does, talk to your doctor before starting this supplement to avoid health risks and complications. Additionally, use caution if taking this supplement at the same time as another supplement that also contains vitamins and minerals, as it’s possible to suffer negative health effects from too-high nutrient doses.



When shopping around for a good testosterone booster, which manufacturer you purchase from can make a huge difference. Different supplement companies produce products with a wide variety of quality levels. Other things like customer support and shipping reliability can vary a lot between companies. If you’re looking for real results, it can be well worth it to pick a product from a trustworthy manufacturer.

The manufacturer of this testosterone booster is Progene Healthcare. This company has offices in both Cincinnati, Ohio and New York, New York, but customers are directed to seek customer support with and to send their returns to the Ohio location. Progene Healthcare has received an A+ rating from the Better Business Bureau. The company makes no other additional information about itself available online. Although the company doesn’t have a very substantial public image, it seems trustworthy.


How Progene Works?

The formula for this testosterone booster has so many components that it would take far too long to explain every single pathway through which this supplement works. The gist of it is that the supplement provides testosterone precursors so that your endocrine system can convert them into testosterone. There are also essential vitamins and minerals that your endocrine system needs to function properly. When testosterone precursors and endocrine-optimizing nutrients are combined, your body can easily create extra testosterone.

The four ingredients that are the most likely to have the greatest effect on testosterone levels are DHEA, Panax Ginseng, Tongkat Ali, and Zinc. There are a handful of others that contribute a smaller magnitude of effect. This product will work the best if you follow the recommendation of two caplets daily. Perhaps take one with breakfast and one with dinner. Taking the product without food can cause nausea due to the Zinc content.


Ingredients of Progene

This supplement has a much longer ingredients list than your average testosterone booster. These ingredients include essential nutrients, botanical extracts, and more. The essential nutrients are Biotin, Folate, Niacin, Pantothenic Acid, Riboflavin, Thiamin, Vitamin A, Vitamin B12, Vitamin E, Vitamin B6, and Zinc. The plant extracts and powders in this product include Damiana Leaf, Eleuthero Root, Guarana Seed Extract, Jamaican Ginger Root, Licorice Root, Mucuna Pruriens Seed, Muira Puama Extract, Nutmeg Seed, Oat Straw Extract, Panax Ginseng Extract, Sarsaparilla Root, Saw Palmetto Berry Extract, Stinging Nettle Extract, Tienchi Ginseng Root, Tinospora Cordifolia Leaf, Tongkat Ali Extract, Tribulus Terrestris Root, and Withania Somnifera Root. Other types of ingredients in the formula include DHEA, L-Arginine, and Lycopene.

Out of all the essential nutrients present in Progene, Zinc is arguably the best addition. There are many studies showing that taking a supplement with Zinc increases your testosterone levels. It’s especially potent if your Zinc levels are too low to begin with. There is 15 milligrams, or 100% DV, of Zinc in each serving of this product.

There are several other essential nutrients that may be effective for increasing testosterone. One study found that male rats with a Vitamin B6 deficiency had significantly reduced testosterone levels, so the Vitamin B6 in Progene could increase levels. Vitamin B12 deficiency is common in those with certain disorders of the endocrine system, so it’s possible that taking Vitamin B12 could improve endocrine function including testosterone production, but this is not clinically proven and is merely a hypothesis. A couple of studies have found that Vitamin E improves testosterone levels in male rats, but there have been some conflicting results. Each serving of this supplement contains 10 milligrams (500% DV) of Vitamin B6, 30 micrograms (100% DV) of Vitamin B12, and 30 IU (100% DV) of Vitamin E.

The other nutrient ingredients in this formula (Biotin, Folate, Niacin, Pantothenic Acid, Riboflavin, Thiamin, and Vitamin A) are not likely to contribute to the testosterone-boosting effects. These vitamins have not been linked to testosterone levels or the endocrine system. However, they can still provide other unrelated health benefits, such as improved energy levels. In one serving of Progene, there are 300 micrograms (100% DV) of Biotin, 400 micrograms (100% DV) of Folate, 30 milligrams (150% DV) of Niacin, 10 milligrams (100% DV) of Pantothenic Acid, 1.7 milligrams (100% DV) of Riboflavin, 1.5 milligrams (100% DV) of Thiamin, and 5,000 IU (100% DV) of Vitamin A.

Although most of the botanicals in this testosterone booster are likely to be useless, a couple stand out as being most effective. These are Panax Ginseng Extract followed by Tongkat Ali Extract. There is good evidence that these plant extracts can increase testosterone levels.

There are a few plant ingredients in this product that may or may not be effective. These are Jamaican Ginger Root, Saw Palmetto Berry Extract, and Stinging Nettle Extract. The Jamaican Ginger Root can potentially increase testosterone, at least in rat studies. The other two plants have shown results that may imply that they increase testosterone. More research is needed on these ingredients to be sure of their testosterone effects, or lack thereof.

The least helpful of the plant-based ingredients in Progene are Damiana Leaf, Eleuthero Root, Mucuna Pruriens Seed, Muira Puama Extract, Nutmeg Seed, Oat Straw Extract, Sarsaparilla Root, Tienchi Ginseng Root, Tribulus Terrestris, and Withania Somniferia Root. All of these ingredients have little to no evidence that they affect testosterone levels or the endocrine system in general.

Strangely, a couple of ingredients have been included in the Progene formula that could actually decrease testosterone levels. These ingredients are Licorice Root and Tinospora Cordifolia Leaf. Studies done on humans and rats prove that these plants have a negative effect on testosterone. However, the amounts of these ingredients in each serving of the supplement is probably small enough that the testosterone-reducing effects are negligible or absent.

There are three ingredients that don’t fit into the categories of nutrient or botanical, and these are DHEA, L-Arginine, and Lycopene. There’s 50 milligrams of DHEA per serving, and there is some limited evidence that this testosterone precursor can increase actual testosterone levels when taken by mouth. L-Arginine is also said to be a testosterone precursor, but there are currently no studies that show that taking it orally increases testosterone levels. In fact, one study done on rats found that taking L-Arginine actually decreased testosterone. Lycopene, a chemical found in tomatoes, does not have any evidence that it affects testosterone levels.

Another word on DHEA: This is a banned substance in sports organizations. Don’t take this product if you are a professional or semi-professional athlete or bodybuilder. If you are a hobbyist athlete or bodybuilder who does not participate in any competitions, then it can be a suitable supplement.

Even for casual athletes who don’t need to worry about substance regulations, DHEA is still not an ideal ingredient for testosterone boosters. Unlike more natural substances like Zinc that are proven to increase testosterone, DHEA is a lab-made chemical that can cause potentially dangerous side effects. These effects can include irregular heartbeat, elevated blood pressure, problems with the reproductive system, and insomnia. Studies show that DHEA can also increase your risk of more serious medical problems later in life. The dosage of DHEA present in this supplement may be enough to bring on these negative effects.



One of the biggest advantages of this testosterone booster is how many vitamins and minerals it contains. As mentioned earlier, these include Biotin, Folate, Niacin, Pantothenic Acid, Riboflavin, Thiamin, Vitamin A, Vitamin B12, Vitamin E, Vitamin B6, and Zinc. Although Zinc is the only among these ingredients that is proven to increase testosterone levels when taken by mouth, the presence of so many other nutrients is still a benefit. The many B-vitamins can help improve your energy levels. All of the nutrients in this formula provide too many health benefits and are important to too many bodily systems to go into detail about all of them here.

The second most notable advantage of taking this supplement is that it contains multiple testosterone precursors. Specifically, these precursors are L-Arginine and DHEA. Your body takes these substances and turns them into testosterone. Although L-Arginine hasn’t been scientifically proven to boost testosterone levels when taken by mouth, it’s still an advantage that this has been included in the formula. Not only may it still potentially increase testosterone despite not being scientifically proven yet, but it also confers other health benefits such as improved blood flow and nitric oxide, which are benefits that are likely to be of interest to people looking to increase their testosterone for fitness reasons.



Certificates can give you clues about the quality of a product or a company. They can be issued by institutions dealing with safety standards, medicine, science, or sports. Product certificates are usually featured on the packaging. Company certificates, if existing, are generally found on the manufacturer’s website. A testosterone booster with certifications may be more safe or effective than a testosterone booster without any.

The product Progene doesn’t have any certificates to its name. Neither does the company that makes it. However, the manufacturer’s website features one safety certificate. It is a certificate proving that the website uses a secure mode of connection, so you can be confident that your financial details will remain private when purchasing online. Note that this product’s lack of certificates aren’t necessarily an indication of poor quality, only that it hasn’t received much attention yet.



Customer reviews, also known as testimonials, are an ideal way to get a feel for how well a product will work for you. Aside from a simple star rating, reviews can provide you with additional information you might not get just from reading a product description. This supplement has received mostly positive reviews from online customers. Here are some actual reviews to help you be well-informed:

Been taking Progene for about a year now. I definitely feel a difference when I’m taking it vs. when I forget to take it. Working out to get back into shape- been helping a lot there… more energy, better results and amazingly, not sore like I used to be after my personal trainer drills me. – Ryan D., consultant in Denver, CO, USA

I like the product and when I take it I feel a difference. However, the bottle I ordered had a short expiration date of one month. I’m not sure if stock is being rotated. – Larry V., engineer in Queens, NY, USA


Awards & Media Coverage

Some organizations and publications that deal with sports medicine issue awards for sports supplements. This includes testosterone boosters such as Progene. If a testosterone booster has been issued an award, it indicates that it’s probably high-quality and reliable. Aside from awards, a supplement may have been the focus of other forms of media attention, such as news segments or celebrity endorsements. These other types of media coverage tell you that a product is well-known.

Progene has not received any meaningful media coverage. The product has not received any awards, either. Even though media coverage can mean a supplement is high quality, this supplement’s lack of media coverage doesn’t necessarily mean that it’s lower-quality. It still may provide you with the results you’re looking for.


Money-back Guarantee

Everyone’s body reacts differently to different ingredients. This is why it can sometimes be a challenge to find a testosterone booster that works for you. It’s very convenient when a company offers a money-back guarantee for their product. Such a guarantee means that in the event that the product doesn’t work for you, you will not have lost your money. If you don’t have experience with testosterone boosters and thus don’t know which ingredients work for you personally, considering purchasing one whose manufacturer offers a money-back guarantee.

It’s easy to get your money back if you’re not satisfied with this product. Contact customer support within 30 days of the original date of purchase to begin the process of returning your order. You can get a refund even if the package is empty, so be sure to try out the supplement to the greatest extent that you can. However, any order originating from a subscription plan is non-refundable, so if after the free trial you still aren’t sure whether it’s working for you, perhaps you should cancel your membership and purchase a bundle a-la-carte instead. This way, you can continue to assess how well it’s working yet maintain the possibility of getting a refund.



Shopping online offers a lot of convenient advantages. For example, shopping online gives you a much wider range of products to choose from, and you can shop from the comfort of your own home, no travel required. However, one less-convenient aspect of purchasing testosterone boosters on the internet is that you will often have to pay a fee for shipping and handling. Plus, different vendors have different shipping policies, so finding a convenient place to buy your product of choice can sometimes be a hassle if you want to spend the least money.

When purchasing a one-month supply, shipping and handling is free. However, three-month and six-month supplies entail a shipping charge of $9.95. The 20-count sample that is available requires a payment of $4.95 for shipping and handling. Subsequent subscription orders require a shipping and handling charge of $9.95 every other month. However, after your third subscription order, shipping will be free of charge.


Customer Support

Among the many factors that go into purchasing a testosterone-increasing supplement is the availability of customer support. Find out what a company’s options are for customer support before making a purchase. After all, if a company has sub-par, unavailable, or unhelpful customer service, your questions and concerns may not end up being answered. Additionally, a total lack of a customer support department might indicate that the product is a scam.

This supplement is a good choice if you prioritize access to customer support. The manufacturer of this testosterone booster offers a toll-free number for reaching their customer service department. If you rather send an e-mail, that option is open as well. Note that this is only true of the Progene Healthcare website. The availability of customer service, as well as available contact methods, will differ if you purchase the supplement somewhere other than here.


Safe & Secure Checkout

Although most shopping websites you will easily come across nowadays are reliable, there still may be some that are less reliable. An important aspect of online shopping safety is that of a secure connection. With a secure connection, your personal and financial details that are entered at checkout will remain safe from malicious third-parties. Ensure that a website uses a secure HTTPS connection before buying.

If you purchase this product directly from the manufacturer, your personal details will be secure. The website for Progene Healthcare features a RapidSSL certificate. RapidSSL is an organization that offers secure website encryption services. They also issue certificates that guarantee a website uses a secure connection. If you’re buying the supplement from a third-party retailer, check that the website uses a secure connection before buying.


Pricing & Free Trial

The manufacturer offers various pricing schemes for this supplement. The first type of pricing model is the bundle. The bundle options include a one-month supply for $59.95, a three-month supply for $129.95, or a six-month supply for $209.85.

The other type of pricing model is the manufacturer’s subscription program. You first enroll in this subscription by requesting a free 10-day supply sample, for which you only need to pay $4.95 for shipping and handling. Requesting the sample automatically enrolls you in the subscription, so if you don’t like the product after trying it, you must cancel your membership before the trial period is over to avoid the bimonthly charges that are to come. If you don’t cancel, you’ll receive an automatic refill every two months, and you will be charged $89.95 bimonthly. Shipping and handling for subscription orders costs $9.95 until after the third shipment, when shipping and handling will become free.

Progene is somewhere around mid-range price, compared to other testosterone boosters. In terms of cost per day, taking into account shipping charges, the best deal is to purchase the six-month supply bundle. However, some customers may find that the convenience of having automatic refills is worth paying a little extra.






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