Blue Gene

Blue Gene by Controlled Labs Review – Can This Product Increase Your Endurance & Stamina?

What Is Blue Gene?

Blue Gene is a dietary supplement marketed as a testosterone booster. It contains a wide variety of nutrients, such as Niacin; various plant extracts, including Grape Seed Extract and Ginkgo Biloba Extract; and other compounds such as L-Carnitine and GlycoCarn. The recommended serving is five tablets daily. The most common size container for this supplement is 150 tablets, which is a thirty-day supply.

The makers of Blue Gene claim that it increases endurance and stamina. It also purportedly optimizes muscle recovery and hormone levels. The formula is free of stimulants and banned substances. This supplement has a moderate amount of scientific evidence to back up its claims. Some of its ingredients have more robust scientific backing than others.



The manufacturer of this supplement is a company called Controlled Labs. They are based in the United States. Little other general company information is available online. The city where headquarters are located, date of founding, and other miscellaneous facts are unavailable. If you prefer to purchase from companies who are more transparent about who they are, perhaps a different supplement would be more ideal.

Although not much information about the company itself is available, information is available about their manufacturing practices. It is important to purchase products that meet official standards for cleanliness, safety, and legality. Fortunately, Controlled Labs is very qualified in this area. Their manufacturing facility is certified for good manufacturing practices and inspected by the FDA. Their products are certified by the NSF to be completely free of all athletic banned substances.


How Blue Gene Works?

Each testosterone booster supplement works in unique ways depending on its ingredients. An ideal testosterone booster is proven to work effectively. Blue Gene works thruogh various pathways for maximum efficacy.

This supplement functions in many different ways, due to its large and varied ingredient list. First off, the tablets contain Grape Seed Extract, Griffonia Simplicifolia Extract, Apigenin, Luteolin and Niacin. The manufacturer claims that these ingredients work in synergy to improve circulation and boost levels of testosterone and natural growth hormone. Grape Seed Extract, Griffonia Simplicifolia Extract, and Niacin have all been shown in studies to improve bloodflow. Niacin seems to be the only one of these ingredients that has scientific proof behind the claim that it can boost testosterone.

The second synergistic ingredient relationship is Quercetin and Gingko Biloba, which the manufacturer claims work together to increase circulation and endurance. There is some limited scientific evidence suggesting that Quercetin can help improve blood flow. As for Gingko Biloba, there is a moderate amount of evidence behind this same claim. Overall, Blue Gene is a reasonably reliable supplement for its stated purposes.


Ingredients of Blue Gene

This supplement offers an impressive array of ingredients. Most of them should not cause side effects for the majority of people, and are safe to take. The ingredients include Niacin, Sodium, Blue C Complex, L-Carnitine, Cissus Quadrangularis Extract, Cassia Grandis Extract, Trichilia Catigua Extract, GlycoCarn (Glycine Propionyl-L-Carnitine Hydrochloride), Quercetin, Ginkgo Biloba Extract, Grape Seed extract, Epimedium Sagittatum Extract, Coenzyme Q-10, Griffonia Simplicifolia Extract, Chamomile Flower Extract, Perilla Frutescens Extract, and various non-active ingredients. Some of the ingredients listed here are part of proprietary blends. Therefore, the exact amounts of each ingredient in this product are unknown.

Niacin – it is also known as Vitamin B3. This nutrient is required by the body for circulation and hormone production. Niacin can be found in many foods such as yeast, meat, fish, eggs, milk, beans, cereal grains, and green vegetables. This supplement contains 50mg, or 250% DV, Niacin per five tablets. The Niacin in these tablets is in the form of Niacinamide.

Sodium – it is in the form of Sodium Bicarbonate, what most of us know as baking soda. The manufacturer claims that Sodium Bicarbonate acts as a hydrogen buffer, leading to reduced fatigue and enhanced recovery. There is a small amount of evidence to support this; one study found that taking Sodium Bicarbonate one or two hours before exercise improves performance. Blue Gene contains 41mg, or 2% DV, Sodium per serving.

The Blue C Complex – this is a proprietary blend. The supplement has 4050mg of the blend per serving. Ingredients in the blend include L-Carnitine, Cissus Quadrangularis Extract, Cassia Grandis Extract, Trichilia Catigua Extract, and GlycoCarn.

L-Carnitine – it is an amino acid that the body produces naturally. The body uses this nutrient for producing energy. This protein building block is important for muscle movement, heart function, brain function, and many other bodily processes. The manufacturers of this supplement claim that the inclusion of this ingredient allows for better recovery from intense training. However, there is little or no scientific evidence behind this claim.

Cissus Quadrangularis – it is a perennial plant of the grape family, native to the area of India, Bangladesh, and Sri Lanka. It has been used by native peoples in traditional medicine. The manufacturers of Blue Gene claim that Cissus Quadrangularis Extract is an anti-catabolic compound that improves the function of tendons and ligaments. There is no scientific evidence behind this. However, one preliminary study found that Cissus Quadrangularis Extract supplementation aided in weight loss.

Cassia Grandis – it is a flowering plant from the legume family, native to Latin America. The makers of this supplement claim that Cassia Grandis Extract helps muscles receive more oxygen, among other claims. There is no proof behind this.

Trichilia Catigua – it is a flowering plant, a distant cousin of the mahogany tree. Controlled Labs claims that this ingredient, like Cassia Grandis Extract, aids muscles in receiving oxygen. Although this plant has been used historically in folk medicine, there is little to no scientific research on it.

GlycoCarn – is the trademark name of Glycine Propionyl-L-Carnitine Hydrochloride. This trademark belongs to Sigma-Tau HealthScience. This ingredient is clinically proven to have many benefits. These benefits include increasing nitric oxide in the bloodstream, increasing blood flow, increasing cellular energy, improving mitochondrial metabolism, reducing muscle tissue damage, toxin removal, and improving muscle recovery. GlycoCarn has also been observed to increase L-Carnitine concentrations in muscle fibers.

Blue Sky Complex – this complex features Quercetin, Ginkgo Biloba Extract, Grape Seed Extract, Epimedium Sagittatum Extract, Coenzyme Q-10, Griffonia Simplicifolia Extract, Chamomile Flower Extract, and Perilla Frutescens Extract. There are 2200mg of this blend in each serving of five tablets.

Quercetin – is a flavonoid, or a plant pigment that has health benefits. Natural sources of Quercetin include red wine, onions, green tea, apples, and berries. Quercetin has some scientific research proving that it improves circulation and has antioxidant effects.

Gingko Biloba – is a tree with fan-shaped leaves, native to Asia. The main effect of the Gingko Biloba Extract included in this supplement is that it improves blood circulation. There is substantial scientific support for this claim.

Grape Seed Extract – it is present in this supplement, and it is a source of flavonoids. The makers of this supplement claim that the Grape Seed Extract in the supplement improves circulation. However, there is little to no scientific support for this. However, the flavonoids in Grape Seed Extract have antioxidant effects, lower bad cholesterol levels, relax blood vessels, and reduce the risk of heart disease.

Epimedium Sagittatum – is a variety of Horny Goat Weed, which is a genus of flowering plants native to China. Epimedium Sagittatum Extract contains chemical such as Icariin, which has the potential to improve blood flow. There is a moderate amount of scientific support behind Controlled Labs’ claims for this ingredient.

Coenzyme Q-10 – it is a vitamin-like substance that is required by many organs and chemical reactions of the body. It is most commonly found in the heart, liver, pancreas, and kidneys, and food sources include meat and seafood. Its functions include antioxidant activity and providing energy to cells. Scientific reasoning supports supplementation with Coenzyme Q-10 for increasing cellular energy. Certain diseases, such as high blood pressure, periodontal disease, high blood pressure, and muscular diseases are associated with low levels of this substance.

Griffonia Simplicifolia – is a woody shrub, found in West and Central Africa. Controlled Labs claims that this ingredient contributes to the supplement’s effects of increasing blood flow, testosterone levels, and natural growth hormone levels. There is no scientific evidence for these claims. However, Griffonia Simplicifolia Extract does contain 5-HTP, a chemical used in the brain as a neurotransmitter. Supplementing with 5-HTP can improve mood and sleep.

Chamomile – is an herb with daisy-like flowers, found throughout Europe. Chamomile Flower Extract contains substances such as Apigenin that seem to have a relaxing and anti-inflammatory effect on the body. There does not seem to be any scientific support for the manufacturer’s claims that the Apigenin from Chamomile Flower Extract regulates hormones or improves circulation.

Perilla Frutescens – is an herb, a member of the mint family. It is used in traditional Asian cuisines. The purpose of including Perilla Frutescens Extract in this supplement is unclear. Perilla Frutescens Extract contains chemicals that might decrease swelling and asthma symptoms.

The vast majority of dietary supplements contain non-active ingredients. These can include anti-caking agents, flavors, dyes, preservatives, binders, fillers, and more. Blue Gene’s inactive ingredients include Dicalcium Phosphate, Stearic Acid, Croscarmellose Sodium, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Hydroxypropyl Methylcellulose, Polyethylene Glycol, Blue #1, and Titanium Dioxide.



Blue Gene is among the more expensive of testosterone boosters. However, you may find that it is worth the price for you, because it carries some advantages over other similar supplements. The first main advantage is that it has a very wide variety of ingredients. Between plant extracts, nutrients, amino acids and more, there are plenty of pathways for your body to receive the benefits.

The other main reason why you might choose this supplement over other similar ones is that it has a good amount of science behind its claims. This is something that cannot be said for every supplement on the market; some are simply snake oil. However, Blue Gene has science and clinical evidence behind many of its ingredients. Not all of the ingredients are scientifically supported, but many are. For example, the ingredient Niacin is known to science to play a part in testosterone production.



One indicator of the quality of a dietary supplement is the presence of associated certifications. Certifications can demonstrate quality, safety, and efficacy, and they can be granted by scientific institutions, medical organizations, quality control programs, and other bodies. The product itself does not have any certificates associated with it. However, the manufacturer of this supplement does have some certificates.

SiteLock is a global leader in providing independent network security certification. The Controlled Labs website is certified with SiteLock. The website is verified to be spam-free, malware-free, and secure. You can be confident that purchasing from this website is completely safe.

The Natural Products Association is the country’s oldest and largest nonprofit organization dealing with the natural products industry. Products that they deal with include foods, health and beauty aids, and dietary supplements. Controlled Labs products are certified with the Natural Products Association for good manufacturing practices.



Real customer reviews and testimonials are a great way to get an accurate assessment of the quality of a product. Blue Gene seems to garnish mostly positive reviews online. Here are a few reviews from real customers:

My favorite supplement. gives me an abundance of energy in the gym. saw extraordinary gains this month while taking blue gene.

– Richard B., Houston, TX

The only thing I felt was less sore the next day after my workout. I don’t know if that justifies the price you have to pay for 2 bottles. Will not buy again.

– Peter G., Los Angeles, CA

Overall a very good product. About one week from the end of a two bottle run. Getting nice recomp effects and am leaning out while staying at around 200lbs. The sweet spot is definitely two bottles (60 days) as I’ve seen more results in the 1st few weeks of the 2nd bottle than in the whole 1st bottle. The only negative is I got a mild increase in acne towards the end of my run.

– Robert R.,  Atlanta, GA

Looking for the ultimate plateau breaker? Well this is it! I see a lot of improvements in the little things that collectively add up to make the big difference. I saw better recovery, endurance, strength, focus/intensity, joint support, harder/fuller muscles, etc. No sides. I highly recommend this.

– Alfred P., Charlotte, NC

Good product when you only cycle the first bottle, running a second cycle created a bloat to my appearance and I had to work hard to get rid of it. Only use one bottle, did not go for a second cycle.

– Michael S., San Francisco, CA


Awards & Media Coverage

One way of assessing the quality of a product is to take a look at what awards and media coverage it has received. Awards can be from magazines, websites, medical organizations, and scientific institutions. Media coverage could be in the form of articles, videos, or being spotlighted by a blog or website. When a product has awards and media coverage, you know that it is well-known.

The product does not have any awards or other types of media coverage associated with it. If purchasing a very well-known product is important to you, a different testosterone booster may be more ideal. However, the manufacturer of the supplement, Controlled Labs, has received a small amount of media attention. At least ten of their products have been nominated for the supplement awards at BodyBuilding.Com. This lets you know that Controlled Labs is not a no-name company that you should be wary of.


Money-back Guarantee

When deciding on an online retailer, one aspect to consider is their return and refund policy. Many people like to be able to try out a new product without yet fully committing to the full purchase price. Although you can buy this supplement from the manufacturer, it is also available at other retailers. Therefore, your money-back options may vary widely.

Controlled Labs has an excellent money-back policy. If you’re unsatisfied with your purchase, you can send the unused portion in the original container back to the manufacturer within thirty days of purchase. You will receive a 105% refund. In other words, you will receive back the purchase price plus an additional 5% of the purchase price. You should get your refund within three weeks.



When you purchase Blue Gene directly from Controlled Labs, shipping is affordable, quick, and versatile. The company ships to every country in the world with the exceptions of Nigeria, Australia, South Africa and Indonesia. The shipping charge is $5.99 for United States orders and $19.99 for international orders, no matter how many items are in your order. Your order should take four to five business days to arrive after you place the order. Your products will be shipped to you in a plain, unmarked box.

Controlled Labs also has flexible payment options. Most online retailers accept credit and debit cards including MasterCard, VISA, and American Express. Controlled Labs also accepts payment via PayPal, check, and money order. When paying via check or money order, you will have to wait until your payment is received and processed before your order is shipped.


Customer Support

Shopping online is ideal because of its convenience and speed. For many people, customer support is an important aspect of shopping online. Customer support is very useful when you have questions or comments about your order. Without a satisfactory customer service department, you may find yourself stuck with a testosterone booster you don’t like or don’t know how to use correctly. Before deciding on an online retailer, consider the quality and availability of their customer support before placing your order.

It seems that the only option for customer support at Controlled Labs is sending them an e-mail. There does not seem to be a phone number that you can call for more immediate assistance. If having a company phone number to call is very important to you, consider buying this supplement through a different retailer that has one. Other retailers may have different options for reaching customer support.


Safe & Secure Checkout

When shopping online, it’s a good idea to pay attention to your safety. One aspect of your safety is the safety of your personal information and financial details. When you purchase Blue Gene directly from the manufacturer, the checkout process features HTTPS. However, the availability of HTTPS can vary if you purchase the product from other websites or companies.

For those who don’t know, HTTPS stands for Hypertext Transfer Protocol Secure. This is a method of internet connection that keeps your data safe. Without HTTPS, malicious third parties may be able to access your data. When this data includes things like personal information and financial details, the information can be used to commit identity theft or fraud.



When purchasing supplements, the price of taking it is usually a factor in making a purchase decision. If a supplement is expensive then ideally it should be worth the price. If a supplement is inexpensive, check to make sure that it’s not low-quality. Additionally, pay attention to the serving size and servings per container. You may think that a large bottle of pills is a good deal, but if you are instructed to take two, three, or even four pills per day, then that drives up the daily cost of taking that supplement.

Blue Gene is on the pricier side when it comes to testosterone boosters. A 150-tablet bottle contains 30 servings, which is a one-month supply. The manufacturer’s website offers this one-month supply for around $77.99, though prices may fluctuate. However, the supplement has been spotted at third-party retailers for as little as $44.99. If you’re concerned about getting a good deal on this product, consider purchasing it from a website or store that is not the manufacturer.






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